Text of a lecture to the Sphex Club in Lynchburg. Beyond the Drosophila by Dr. Jeffrey W. Wilson explores the complexity of genetic inheritance and its implications on human health. Organized into personal anecdotes and scientific discussions, the paper delves into genotype and phenotype relationships, the role of family history in understanding genetic predispositions, and the impact of environmental factors on genetic expression. Key points include the importance of genomics in modern medicine, the interaction between genetics and environment, and the potential for personalized medicine.