Text of a lecture delivered to the Sphex Club in Lynchburg. Nina Salmon's talk focuses on the phenomenon of handedness, emphasizing the marginalization of left-handed individuals by the majority right-handed culture. She explores the etymology of language surrounding left-handedness, its causes, prevalence, and societal biases. By comparing left-handedness to other biological and physical minority traits, Salmon highlights cultural disadvantages and misconceptions. The talk concludes with an interactive component, revealing a higher prevalence of left-handedness among the SPHEX Club members than in the general population, suggesting potential benefits in creativity and intelligence for left-handed individuals.